{"id":2119,"date":"2026-05-14T08:53:57","date_gmt":"2026-05-14T08:53:57","guid":{"rendered":"https:\/\/drsoniafawad.com\/?p=2119"},"modified":"2026-05-14T08:53:57","modified_gmt":"2026-05-14T08:53:57","slug":"lipedematous-alopecia-topical-and-intralesional-steroids-still-first-line-donovan-hair-clinic","status":"publish","type":"post","link":"https:\/\/drsoniafawad.com\/?p=2119","title":{"rendered":"Lipedematous Alopecia: Topical and Intralesional Steroids Still First Line \u2014 Donovan Hair Clinic"},"content":{"rendered":"<p><br \/>\n<\/p>\n<div data-sqsp-text-block-content=\"\">\n<p class=\"\" style=\"white-space:pre-wrap;\">Lipedematous scalp is a rare cutaneous condition characterized by a boggy, thick, and spongy consistency of the scalp due to thickening of the subcutaneous adipose tissue. In these conditions, the overlying skin usually appears normal, though patients often report symptoms of pain, paresthesia, or a localized \u201cpressure\u201d sensation.<\/p>\n<p>When this structural thickening is accompanied by hair loss\u2014the condition is termed lipedematous alopecia. The exact pathogenesis remains unclear, but it is hypothesized that the expanded fat layer may mechanically compress hair follicles or disrupt the dermal microenvironment necessary for healthy hair growth.<\/p>\n<h3 style=\"white-space:pre-wrap;\"><strong>Our New Study of Lipedematous Alopecia Highlights Areas of Treatment Success<\/strong><\/h3>\n<p class=\"\" style=\"white-space:pre-wrap;\">Our research team performed a systematic review of this challenging condition. We uncovered 33 patients in 23 studies. There were 19 patients with with lipedematous alopecia and 14 with lipedematous scalp. These studies highlight the limited but evolving treatment landscape. Most diagnoses relied on scalp biopsy.\u00a0 This study was led by the great work of the first author, Katya Peri, from McGill University medical school.<\/p>\n<p>Topical and intralesional steroids were among the most effective treatments for lipedematous alopecia, leading to complete responses in about 50 % of patients. The most effective systemic therapies were mycophenolate mofetil with more limited data for other treatments such as hydroxychloroquine and doxycycline.<\/p>\n<p>The full study is published in the International Journal of Dermatology. I congratulate all of our coauthors for their efforts to better understand this fascinating and very much underrecognized condition.<\/p>\n<p class=\"\" style=\"white-space:pre-wrap;\"><strong>Reference<\/strong><\/p>\n<p>Peri K et al. Int J Dermatol 2026<\/p>\n<\/div>\n<p><br \/>\n<br \/><a href=\"https:\/\/donovanmedical.com\/hair-blog\/la-ls\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Lipedematous scalp is a rare cutaneous condition characterized by a boggy, thick, and spongy consistency of the scalp due to thickening of the subcutaneous adipose tissue. In these conditions, the overlying skin usually appears normal, though patients often report symptoms of pain, paresthesia, or a localized \u201cpressure\u201d sensation. When this structural thickening is accompanied by hair loss\u2014the condition is termed lipedematous alopecia. The exact pathogenesis remains unclear, but it is hypothesized that the expanded fat layer may mechanically compress hair follicles or disrupt the dermal microenvironment necessary for healthy hair growth. Our New Study of Lipedematous Alopecia Highlights Areas of Treatment Success Our research team performed a systematic review of this challenging condition. We uncovered 33 patients in 23 studies. There were 19 patients with with lipedematous alopecia and 14 with lipedematous scalp. These studies highlight the limited but evolving treatment landscape. Most diagnoses relied on scalp biopsy.\u00a0 This study was led by the great work of the first author, Katya Peri, from McGill University medical school. Topical and intralesional steroids were among the most effective treatments for lipedematous alopecia, leading to complete responses in about 50 % of patients. The most effective systemic therapies were mycophenolate mofetil with more limited data for other treatments such as hydroxychloroquine and doxycycline. The full study is published in the International Journal of Dermatology. I congratulate all of our coauthors for their efforts to better understand this fascinating and very much underrecognized condition. Reference Peri K et al. Int J Dermatol 2026 Source link<\/p>\n","protected":false},"author":1,"featured_media":2120,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-2119","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-hair-fall-dandruff"],"_links":{"self":[{"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=\/wp\/v2\/posts\/2119","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2119"}],"version-history":[{"count":0,"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=\/wp\/v2\/posts\/2119\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=\/wp\/v2\/media\/2120"}],"wp:attachment":[{"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2119"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2119"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2119"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}