{"id":2221,"date":"2026-05-14T11:07:32","date_gmt":"2026-05-14T11:07:32","guid":{"rendered":"https:\/\/drsoniafawad.com\/?p=2221"},"modified":"2026-05-14T11:07:32","modified_gmt":"2026-05-14T11:07:32","slug":"stopping-jak-inhibitors-for-pregnancy-what-happens-to-hair-in-aa-donovan-hair-clinic","status":"publish","type":"post","link":"https:\/\/drsoniafawad.com\/?p=2221","title":{"rendered":"Stopping JAK Inhibitors for Pregnancy: What Happens to Hair in AA? \u2014 Donovan Hair Clinic"},"content":{"rendered":"<p><br \/>\n<\/p>\n<div id=\"post-69507c7b7dcf0a469d686e18\">\n<p>    <!--POST TILE--><\/p>\n<p class=\"meta\">\n      <a href=\"https:\/\/donovanmedical.com\/hair-blog\/aa-pregnancy-jak-inhibitors\"><time datetime=\"2026-02-15\">February 15, 2026<\/time><\/a><\/p>\n<p>    <!--MAIN CONTENT--><\/p>\n<div class=\"sqs-layout sqs-grid-12 columns-12\" data-layout-label=\"Post Body\" data-type=\"item\" data-updated-on=\"1766882467201\" id=\"item-69507c7b7dcf0a469d686e18\">\n<div class=\"row sqs-row\">\n<div class=\"col sqs-col-12 span-12\">\n<div class=\"sqs-block html-block sqs-block-html\" data-block-type=\"2\" data-sqsp-block=\"text\" id=\"block-471a615ea0342491189d\">\n<div class=\"sqs-block-content\">\n<div class=\"sqs-html-content\" data-sqsp-text-block-content=\"\">\n<p class=\"\" style=\"white-space:pre-wrap;\"><strong>BACKGROUND &amp; PURPOSE<\/strong><br \/>Janus kinase inhibitors (JAK inhibitors) can help severe alopecia areata (AA) regrow hair. But because safety in pregnancy isn\u2019t fully known, and recommendations are now for women stop treatment when trying to conceive. This often leads to fear of hair loss returning. The <strong>purpose<\/strong> of this study was to describe what happens to scalp hair when JAK inhibitors are stopped for pregnancy \u2014 and what happens after restarting them postpartum.<\/p>\n<p class=\"\" style=\"white-space:pre-wrap;\"><strong>METHODS<\/strong><br \/>Doctors followed 9 women with severe AA through 14 pregnancies. All stopped oral JAK inhibitors before or early in pregnancy. Hair loss severity was measured using the SALT score before treatment, after stopping treatment, and after restarting postpartum.<\/p>\n<p class=\"\" style=\"white-space:pre-wrap;\"><strong>RESULTS<\/strong><br \/>Every woman experienced significant hair loss after stopping treatment. However, once JAK inhibitors were restarted \u2014 usually within 4 months after delivery \u2014 patients regrew their hair, often back to or better than before. <\/p>\n<\/div>\n<\/div>\n<\/div>\n<div class=\"sqs-block image-block sqs-block-image\" data-block-type=\"5\" data-sqsp-block=\"image-classic\" id=\"block-yui_3_17_2_1_1766880210972_153785\">\n<div class=\"sqs-block-content\">\n<div class=\"&#10;          image-block-outer-wrapper&#10;          layout-caption-below&#10;          design-layout-inline&#10;          combination-animation-none&#10;          individual-animation-none&#10;          individual-text-animation-none&#10;        \" data-test=\"image-block-inline-outer-wrapper\" data-sqsp-image-classic-block-layout=\"inline\">\n<figure class=\"&#10;              sqs-block-image-figure&#10;              intrinsic&#10;            \" style=\"max-width:1900px;\">\n<div class=\"image-block-wrapper\" data-animation-role=\"image\">\n<div data-sqsp-image-classic-block-image-container=\"\" class=\"sqs-image-shape-container-element&#10;              &#10;          &#10;        &#10;              has-aspect-ratio&#10;            \" style=\"&#10;                position: relative;&#10;                &#10;                  padding-bottom:46.842105865478516%;&#10;                &#10;                overflow: hidden;-webkit-mask-image: -webkit-radial-gradient(white, black);&#10;              \">\n<p>                <img loading=\"lazy\" data-stretch=\"false\" src=\"https:\/\/images.squarespace-cdn.com\/content\/v1\/5243dccde4b08fd9e4fc92ef\/8a1ba8d2-7b9c-4553-a719-4f225fa9cafe\/Screenshot+2025-12-27+at+4.44.09%E2%80%AFPM.png\" data-image=\"https:\/\/images.squarespace-cdn.com\/content\/v1\/5243dccde4b08fd9e4fc92ef\/8a1ba8d2-7b9c-4553-a719-4f225fa9cafe\/Screenshot+2025-12-27+at+4.44.09%E2%80%AFPM.png\" data-image-dimensions=\"1900x890\" data-image-focal-point=\"0.5,0.5\" alt=\"\" data-load=\"false\" elementtiming=\"system-image-block\" data-sqsp-image-classic-block-image=\"\" width=\"1900\" height=\"890\" sizes=\"auto, (max-width: 640px) 100vw, (max-width: 767px) 100vw, 100vw\" style=\"display:block;object-fit: cover; width: 100%; height: 100%; object-position: 50% 50%\" onload=\"this.classList.add(&quot;loaded&quot;)\" srcset=\"https:\/\/images.squarespace-cdn.com\/content\/v1\/5243dccde4b08fd9e4fc92ef\/8a1ba8d2-7b9c-4553-a719-4f225fa9cafe\/Screenshot+2025-12-27+at+4.44.09%E2%80%AFPM.png?format=100w 100w, https:\/\/images.squarespace-cdn.com\/content\/v1\/5243dccde4b08fd9e4fc92ef\/8a1ba8d2-7b9c-4553-a719-4f225fa9cafe\/Screenshot+2025-12-27+at+4.44.09%E2%80%AFPM.png?format=300w 300w, https:\/\/images.squarespace-cdn.com\/content\/v1\/5243dccde4b08fd9e4fc92ef\/8a1ba8d2-7b9c-4553-a719-4f225fa9cafe\/Screenshot+2025-12-27+at+4.44.09%E2%80%AFPM.png?format=500w 500w, https:\/\/images.squarespace-cdn.com\/content\/v1\/5243dccde4b08fd9e4fc92ef\/8a1ba8d2-7b9c-4553-a719-4f225fa9cafe\/Screenshot+2025-12-27+at+4.44.09%E2%80%AFPM.png?format=750w 750w, https:\/\/images.squarespace-cdn.com\/content\/v1\/5243dccde4b08fd9e4fc92ef\/8a1ba8d2-7b9c-4553-a719-4f225fa9cafe\/Screenshot+2025-12-27+at+4.44.09%E2%80%AFPM.png?format=1000w 1000w, https:\/\/images.squarespace-cdn.com\/content\/v1\/5243dccde4b08fd9e4fc92ef\/8a1ba8d2-7b9c-4553-a719-4f225fa9cafe\/Screenshot+2025-12-27+at+4.44.09%E2%80%AFPM.png?format=1500w 1500w, https:\/\/images.squarespace-cdn.com\/content\/v1\/5243dccde4b08fd9e4fc92ef\/8a1ba8d2-7b9c-4553-a719-4f225fa9cafe\/Screenshot+2025-12-27+at+4.44.09%E2%80%AFPM.png?format=2500w 2500w\" loading=\"lazy\" decoding=\"async\" data-loader=\"sqs\" \/><\/p><\/div>\n<\/p><\/div><figcaption data-sqsp-image-classic-block-caption-container=\"\" class=\"image-caption-wrapper\">\n<div class=\"image-caption\">\n<p class=\"\" style=\"white-space:pre-wrap;\">FIGURE 1 FROM Ogbutor C, Chen L-C, Kalil LL, et al. Discontinuation and restart of Janus kinase inhibitors due to pregnancy in alopecia areata: a case series. <em>Int J Womens Dermatol.<\/em> 2025;11:e218. used with creative commons license. <\/p>\n<\/div>\n<\/figcaption><\/figure>\n<\/p><\/div>\n<\/div>\n<\/div>\n<div class=\"sqs-block html-block sqs-block-html\" data-block-type=\"2\" data-sqsp-block=\"text\" id=\"block-yui_3_17_2_1_1766880210972_154175\">\n<div class=\"sqs-block-content\">\n<div class=\"sqs-html-content\" data-sqsp-text-block-content=\"\">\n<p class=\"\" style=\"white-space:pre-wrap;\"><strong>CONCLUSIONS<\/strong><br \/>Women with AA who must stop JAK inhibitors during pregnancy should be counseled that hair shedding is highly likely. The encouraging news is that restarting treatment after delivery (and after breastfeeding is done) led to meaningful regrowth in all cases. This study highlights the emotional burden these women face and the need for clearer pregnancy-related treatment guidelines in AA.<\/p>\n<p class=\"\" style=\"white-space:pre-wrap;\"><strong>REFERENCE<\/strong><br \/>Ogbutor C, Chen L-C, Kalil LL, et al. Discontinuation and restart of Janus kinase inhibitors due to pregnancy in alopecia areata: a case series. <em>Int J Womens Dermatol.<\/em> 2025;11:e218.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p>    <!--BLOG INJECTION--><\/p>\n<hr \/>\n<p>    This article was written by Dr. Jeff Donovan, a Canadian and US board certified dermatologist specializing exclusively in hair loss. <\/p>\n<p>    <!--CATEGORIES\n\n    \n\n    \n\n    \n--><br \/>\n    <!--SHARE AND LIKE--><\/p>\n<p>    <!--COMMENTS--><\/p><\/div>\n<p><br \/>\n<br \/><a href=\"https:\/\/donovanmedical.com\/hair-blog\/aa-pregnancy-jak-inhibitors\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>February 15, 2026 BACKGROUND &amp; PURPOSEJanus kinase inhibitors (JAK inhibitors) can help severe alopecia areata (AA) regrow hair. But because safety in pregnancy isn\u2019t fully known, and recommendations are now for women stop treatment when trying to conceive. This often leads to fear of hair loss returning. The purpose of this study was to describe what happens to scalp hair when JAK inhibitors are stopped for pregnancy \u2014 and what happens after restarting them postpartum. METHODSDoctors followed 9 women with severe AA through 14 pregnancies. All stopped oral JAK inhibitors before or early in pregnancy. Hair loss severity was measured using the SALT score before treatment, after stopping treatment, and after restarting postpartum. RESULTSEvery woman experienced significant hair loss after stopping treatment. However, once JAK inhibitors were restarted \u2014 usually within 4 months after delivery \u2014 patients regrew their hair, often back to or better than before. FIGURE 1 FROM Ogbutor C, Chen L-C, Kalil LL, et al. Discontinuation and restart of Janus kinase inhibitors due to pregnancy in alopecia areata: a case series. Int J Womens Dermatol. 2025;11:e218. used with creative commons license. CONCLUSIONSWomen with AA who must stop JAK inhibitors during pregnancy should be counseled that hair shedding is highly likely. The encouraging news is that restarting treatment after delivery (and after breastfeeding is done) led to meaningful regrowth in all cases. This study highlights the emotional burden these women face and the need for clearer pregnancy-related treatment guidelines in AA. REFERENCEOgbutor C, Chen L-C, Kalil LL, et al. Discontinuation and restart of Janus kinase inhibitors due to pregnancy in alopecia areata: a case series. Int J Womens Dermatol. 2025;11:e218. This article was written by Dr. Jeff Donovan, a Canadian and US board certified dermatologist specializing exclusively in hair loss. Source link<\/p>\n","protected":false},"author":1,"featured_media":2222,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-2221","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-hair-fall-dandruff"],"_links":{"self":[{"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=\/wp\/v2\/posts\/2221","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2221"}],"version-history":[{"count":0,"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=\/wp\/v2\/posts\/2221\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=\/wp\/v2\/media\/2222"}],"wp:attachment":[{"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2221"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2221"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2221"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}