Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"
Add topic to email alerts
Receive an email when new articles are posted on
Please provide your email address to receive an email when new articles are posted on . “
data-action=”subscribe”>
Subscribe
We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. Back to Healio Key takeaways: Pediatric patients\/parents were asked how often they\/their child experienced 12 EoE-related symptoms and were referred to GI if symptoms were concerning for EoE. Eight patients received a new EoE diagnosis. Through a symptom-based screening approach, 8% to 13.9% of pediatric patients with asthma who were seen in an academic pediatric asthma\/allergy clinic had eosinophilic esophagitis, according to study results. These results were published in The Journal of Allergy and Clinical Immunology: In Practice.
\u201cThese findings highlight that EoE is not an uncommon problem for children with asthma, and there may be a role for screening children with asthma for symptoms of EoE proactively,\u201d Robert E. Becker, MD, pediatric gastroenterologist at Children\u2019s Hospital of Wisconsin and assistant professor of pediatric gastroenterology at the Medical College of Wisconsin, told Healio. In this study, Becker and colleagues assessed 189 pediatric patients (median age, 8.6 years; 58.7% boys; 39.2% Black\/African American; 29.1% white; 16.4% Hispanic\/\u201cLatinx\u201d) with asthma to determine how prevalent EoE is in this population via a modified Pediatric Eosinophilic Esophagitis Symptom Severity v2.0 (PEESSv2.0) questionnaire given in a tertiary care pediatric asthma\/allergy clinic to screen for disease. \u201cThis study was the brainchild of Dr. Diana Lerner, one of the manuscript\u2019s senior authors,\u201d Becker said. \u201cIt is not unusual for patients to have symptoms for years prior to being diagnosed with EoE, so we wondered to what extent EoE was undiagnosed among children and adolescents with asthma.\u201d The parents of patients aged 3 to 6 years completed the survey, whereas patients aged 7 to 17 years completed the questionnaire. The study outlined that the questionnaire asked patients\/parents how often they\/their child experienced 12 EoE-related symptoms: chest pain, heartburn, stomach aches, trouble swallowing, food gets stuck, need fluids to swallow, vomiting, nausea, food comes back up, eats less than others, needs more time to eat and avoids difficult foods. Seventy-two of the 189 subjects (38%) were referred to gastroenterology by the allergists because of symptoms deemed concerning for EoE. Eight patients received a new EoE diagnosis. In the studied population, 8% (95% CI, 5.1%-11.7%) was the total confirmed EoE prevalence, \u201cassuming there were no undiagnosed cases of EoE among non-participants or patients lost to follow-up,\u201d the authors wrote. After accounting for patients who declined participation or were lost to follow-up, researchers projected a prevalence of 13.9% (95% CI, 10.1%-18.4%). \u201cWe found that about 10% of children and teenagers seen in this setting (tertiary care pediatric asthma\/allergy clinic) have EoE,\u201d Becker told Healio. \u201cWe generally know that kids with asthma and allergies have increased risk for EoE, but there have not previously been estimates of this prevalence based on proactive screening.\u201d When compared with those without EoE, those with EoE were similar in age, sex, race, BMI z scores, asthma severity and number of comorbidities. Lastly, researchers reported a significant link between vomiting at screening and an EoE diagnosis, as a larger proportion of those with vs. without EoE reported this symptom (37.5% vs. 1.7%; P = .001). No other individual screening symptoms reached significance. \u201cIn the future, it will be important to know the prevalence of EoE in other clinical settings and to inch toward better understanding of how, when, why and for whom we may screen for symptoms of EoE,\u201d Becker told Healio. For more information: Robert E. Becker, MD, can be reached at rbecker@mcw.edu. Ask a clinical question and tap into Healio AI’s knowledge base.
PubMed, enrolling\/recruiting trials, guidelines
Clinical Guidance, Healio CME, FDA news
Healio’s exclusive daily news coverage of clinical data
Learn more
Add topic to email alerts
Receive an email when new articles are posted on
Please provide your email address to receive an email when new articles are posted on . “
data-action=”subscribe”>
Subscribe
We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. Back to Healio Source link<\/p>\n","protected":false},"author":1,"featured_media":3139,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-3138","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=\/wp\/v2\/posts\/3138","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3138"}],"version-history":[{"count":0,"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=\/wp\/v2\/posts\/3138\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=\/wp\/v2\/media\/3139"}],"wp:attachment":[{"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3138"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3138"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/drsoniafawad.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3138"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}