Christina Applegate is in pain, and she still doesn’t know why.

On a recent episode of her MeSsy podcast with Jamie-Lynn Sigler, the actress shared another possibility she wants to investigate: the breast implants she received after her 2008 double mastectomy.

“And I swear, over the last five years or whatever, I thought, ‘What if they’re leaking and they’re like poisoning me?’” she said.

Could Breast Implants Be Contributing to Applegate’s Symptoms?

Applegate believes she’s “way overdue” to have her implants replaced. She hasn’t said doctors have found a leak, and she doesn’t have confirmation that they’re making her sick. But after years of wondering, she wants to get them checked.


“So, that’s one that I will be looking into because it’s something I’ve thought about,” she said.

It’s a question other women have asked, too. Fatigue, brain fog, and joint pain are among the symptoms people describe as “breast implant illness (BII).” The symptoms are real, but researchers are still working out whether (and how) the implants might be involved.

“At this point, well-designed studies have not shown that breast implants cause MS or other neurological diseases,” breast surgical oncologist Dr. Magdalena Lombardi Plasilova told SheKnows’ sister site Flow Space.

Applegate is experiencing concerning symptoms, though, and is on the hunt for answers. “I don’t know what’s going on in my joints, but I can’t move my right shoulder like at all now. I can’t lift my arm,” she said.

Applegate Is Undergoing More Testing for Her Symptoms

Applegate recently revealed that she had been misdiagnosed with MS, leaving her with even more questions. Her doctors are testing for other conditions, including rheumatoid arthritis, lupus, and Lyme disease. A different diagnosis could change her treatment, but first, she has to get through the testing.

“We’re going into square one, just doing some testing and going one-by-one of the sister diseases to MS,” she told MeSsy listeners earlier this month. “You’ve got RA [rheumatoid arthritis], lupus, Lyme disease, all these things can kind of mimic MS. So now I’m being tested for all that stuff slowly but surely.”

And then there are the unsolicited suggestions. Sigler said she’d received about 150 texts from people recommending doctors or hoping to connect with Applegate. But Applegate said many of those possibilities were already on her radar.

“It’s overwhelming because there’s so many different things that could be going on,” she said.



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